SCHEMBL9799045

SCHEMBL9799045

CON(C)C(=O)Nc1cccc(OCCc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.53
SIRT2 Q8IXJ6 5/20 0.53
NR1H4 Q96RI1 1/20 0.53
NPC1 O15118 2/20 0.49
USP2 O75604 1/20 0.49
KMT2A Q03164 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
FFAR1 O14842 1/20 0.48
NPY5R Q15761 1/20 0.47
MEN1 O00255 1/20 0.46
MAPK1 P28482 1/20 0.46
KDM1A O60341 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10810478 0.94 SIRT2 (0.54) RAB9ASIRT2NR1H4NPC1USP2
SCHEMBL11043173 0.93 FFAR1 (0.58) RAB9ANR1H4NPC1KMT2ASMN1; SMN2
SCHEMBL11037929 0.91 SIRT2 (0.55) RAB9ASIRT2NR1H4KMT2ASMN1; SMN2
SCHEMBL10805177 0.91 RAB9A (0.51) RAB9ASIRT2NPC1USP2KMT2A
SCHEMBL11039230 0.91 SIRT2 (0.45) RAB9ASIRT2NR1H4FFAR1
SCHEMBL11041569 0.91 HPGD (0.53) RAB9ANPC1KMT2ASMN1; SMN2FFAR1
SCHEMBL11044457 0.91 SIRT2 (0.57) RAB9ASIRT2NR1H4NPC1KMT2A
SCHEMBL11041771 0.90 RAB9A (0.55) RAB9ASIRT2NPC1KMT2ANPY5R
SCHEMBL9798961 0.90 MAPK1 (0.46) RAB9ASIRT2NR1H4NPC1KMT2A
SCHEMBL10801844 0.89 SIRT2 (0.56) RAB9ASIRT2NR1H4USP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4490165-A Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds, methods for preparing same and herbicidal use thereof AMERICAN CYANAMID COMPANY (US) 1984-12-25 US claimed
US-4308213-A Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds AMERICAN CYANAMID COMPANY (US) 1981-12-29 US claimed
US-5015762-A Alkoxy substituted ureas as herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
US-4690709-A NONTOXIC AND NONPHYTOTOXIC PHOTOSYNTHESIS INHIBITORS; FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-01 US disclosed
US-4437880-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-03-20 US disclosed
US-4422871-A Aralkylphenylureas and herbicides containing these BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0040859-B1 N'-PHENYL-N-METHYLUREA DERIVATIVES, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-08-03 EP disclosed
US-4309212-A POSTEMERGENCE, FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-01-05 US disclosed
EP-0040859-A1 N'-phenyl-N-methylurea derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-02 EP disclosed