Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799071 | 0.78 | MAPK14 (0.35) | HSD17B10ALDH1A1MAPK14HPGDMAPT | |
| SCHEMBL9726605 | 0.74 | HSD17B10 (0.43) | USP2HSD17B10ALDH1A1MAPK14HPGD | |
| SCHEMBL10425983 | 0.74 | HMGCR (0.39) | ALDH1A1LMNASLC1A2 | |
| SCHEMBL10612114 | 0.74 | HSD17B10 (0.41) | USP2HSD17B10ALDH1A1MAPK14HPGD | |
| SCHEMBL10612118 | 0.74 | HSD17B10 (0.41) | USP2HSD17B10ALDH1A1MAPK14HPGD | |
| SCHEMBL9799165 | 0.73 | USP2 (0.38) | USP2HSD17B10ALDH1A1MAPK14HPGD | |
| SCHEMBL10612928 | 0.72 | USP2 (0.39) | USP2HSD17B10ALDH1A1MAPK14HPGD | |
| SCHEMBL9726787 | 0.72 | HSD17B10 (0.43) | USP2HSD17B10ALDH1A1MAPK14HPGD | |
| SCHEMBL9726502 | 0.70 | HSD17B10 (0.43) | USP2HSD17B10ALDH1A1MAPK14HPGD | |
| SCHEMBL9726834 | 0.70 | HSD17B10 (0.41) | USP2HSD17B10ALDH1A1MAPK14HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |