Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766859 | 0.82 | TRPM8 (0.41) | XBP1TRPM8KMT2A | |
| SCHEMBL9799160 | 0.78 | USP2 (0.38) | MAPK14KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10610225 | 0.74 | LTA4H (0.31) | — | |
| SCHEMBL9726463 | 0.74 | HSD17B10 (0.39) | MAPK14FYNMKNK1KDM4EALDH1A1 | |
| SCHEMBL10608803 | 0.73 | LMNA (0.30) | — | |
| SCHEMBL9799075 | 0.73 | MAPK14 (0.35) | MAPK14FYNMKNK1KDM4EALDH1A1 | |
| SCHEMBL10609609 | 0.72 | MAPK14 (0.36) | MAPK14FYNMKNK1KDM4EALDH1A1 | |
| SCHEMBL9726603 | 0.72 | HSD17B10 (0.38) | MAPK14FYNMKNK1KDM4EALDH1A1 | |
| SCHEMBL10610752 | 0.72 | MEN1 (0.42) | MAPK14FYNMKNK1KDM4EALDH1A1 | |
| SCHEMBL9798947 | 0.70 | HMGCR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |