Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 1/20 | 0.50 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | GSR | P00390 | 2/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440397 | 0.88 | GABRR1 (0.61) | BHMTBHMT2GABRR1GSRSLC7A5 | |
| SCHEMBL6440050 | 0.88 | GABRR1 (0.61) | BHMTBHMT2GABRR1GSRSLC7A5 | |
| SCHEMBL28927957 | 0.86 | GABRR1 (0.41) | BHMTBHMT2GABRR1SLC7A5CYP1A2 | |
| SCHEMBL17164633 | 0.83 | GSR (0.54) | BHMTBHMT2GSRGRM8GRM6 | |
| SCHEMBL2348277 | 0.83 | GABRR1 (0.59) | GABRR1CYP1A2BLM | |
| SCHEMBL5323838 | 0.82 | KMT2A (0.52) | BHMTBHMT2GABRR1GSRSLC7A5 | |
| SCHEMBL602426 | 0.80 | GSR (0.68) | BHMTBHMT2GSRSLC7A5GRM8 | |
| SCHEMBL8068164 | 0.80 | GSR (0.68) | BHMTBHMT2GSRSLC7A5GRM8 | |
| SCHEMBL13410354 | 0.80 | GABRR1 (0.46) | GABRR1CYP1A2BLM | |
| SCHEMBL8234927 | 0.79 | GRIK1 (0.52) | BHMTBHMT2GSRSLC7A5GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412104-A1 | COLD MARKING OF MOLECULES OF PEPTIDIC OR PROTEINIC NATURE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1991-02-13 | — | — | EP | disclosed |
| WO-1989010372-A1 | COLD MARKING OF MOLECULES OF PEPTIDIC OR PROTEINIC NATURE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1989-11-02 | — | — | WO | disclosed |