Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.61 |
| ▸ | BHMT | Q93088 | 1/20 | 0.55 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440050 | 1.00 | GABRR1 (0.61) | GABRR1BHMTBHMT2CYP1A2GSR | |
| SCHEMBL9799241 | 0.88 | BHMT (0.50) | GABRR1BHMTBHMT2CYP1A2GSR | |
| SCHEMBL5323838 | 0.88 | KMT2A (0.52) | GABRR1BHMTBHMT2CYP1A2GSR | |
| SCHEMBL7159534 | 0.86 | LTA4H (0.60) | GABRR1CYP1A2GSRBLMKMT2A | |
| SCHEMBL8068164 | 0.86 | GSR (0.68) | BHMTBHMT2CYP1A2GSRSLC1A3 | |
| SCHEMBL602426 | 0.86 | GSR (0.68) | BHMTBHMT2CYP1A2GSRSLC1A3 | |
| SCHEMBL59989 | 0.84 | BHMT (0.55) | BHMTBHMT2CYP1A2GSRSLC1A3 | |
| SCHEMBL255211 | 0.84 | SLC1A3 (0.65) | BHMTBHMT2CYP1A2GSRSLC1A3 | |
| SCHEMBL13269874 | 0.84 | BHMT (0.55) | BHMTBHMT2CYP1A2GSRSLC1A3 | |
| SCHEMBL17039475 | 0.84 | BHMT (0.55) | BHMTBHMT2CYP1A2GSRSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11622951-B2 | Alpha-aminoadipate for treatment of vision loss and restoring sight | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-20210059969-A1 | ALPHA-AMINOADIPATE FOR TREATMENT OF VISION LOSS AND RESTORING SIGHT | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. | 2021-03-04 | — | — | US | disclosed |
| US-10780070-B2 | Alpha-aminoadipate for treatment of vision loss and restoring sight | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. (US) | 2020-09-22 | — | — | US | disclosed |
| US-20160271091-A1 | Alpha-Aminoadipate For Treatment Of Vision Loss And Restoring Sight | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. | 2016-09-22 | — | — | US | disclosed |
| US-20050152995-A1 | Methods and compositions for promoting axon regeneration and cell replacement therapy | SCHEPENS EYE RESEARCH INSTITUTE, THE | 2005-07-14 | — | — | US | disclosed |
| WO-2005041944-A2 | METHODS AND COMPOSITIONS FOR PROMOTING AXON REGENERATION AND CELL REPLACEMENT THERAPY | SCHEPENS EYE RESEARCH INSTITUTE (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210059969-A1 | ALPHA-AMINOADIPATE FOR TREATMENT OF VISION LOSS AND RESTORING SIGHT | AADAT, PDE6A, PDE6C | GABRR1 522/4885BHMT 658/4885BHMT2 866/4885 |
| US-11622951-B2 | Alpha-aminoadipate for treatment of vision loss and restoring sight | AADAT, PDE6A, PDE6C | GABRR1 522/4885BHMT 658/4885BHMT2 866/4885 |
| US-20160271091-A1 | Alpha-Aminoadipate For Treatment Of Vision Loss And Restoring Sight | AADAT, PDE6A, PDE6C | GABRR1 522/4885BHMT 658/4885BHMT2 866/4885 |
| US-10780070-B2 | Alpha-aminoadipate for treatment of vision loss and restoring sight | AADAT, PDE6A, PDE6C | GABRR1 522/4885BHMT 658/4885BHMT2 866/4885 |
| US-20050152995-A1 | Methods and compositions for promoting axon regeneration and cell replacement therapy | GAP43, BDNF, NGF | GABRR1 318/4885BHMT 2792/4885BHMT2 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.