Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799277 | 1.00 | MAPT (0.49) | MAPTALDH1A1LMNASMN1; SMN2BACE1 | |
| SCHEMBL9799245 | 0.88 | MAPT (0.51) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9799239 | 0.88 | MAPT (0.51) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9799330 | 0.86 | MAPT (0.43) | MAPTALDH1A1LMNASMN1; SMN2BACE1 | |
| SCHEMBL9799326 | 0.86 | MAPT (0.43) | MAPTALDH1A1LMNASMN1; SMN2BACE1 | |
| SCHEMBL9799316 | 0.86 | MAPT (0.49) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9799309 | 0.86 | MAPT (0.49) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9798869 | 0.84 | MAPT (0.54) | MAPTALDH1A1LMNASMN1; SMN2BACE1 | |
| SCHEMBL9798875 | 0.84 | MAPT (0.54) | MAPTALDH1A1LMNASMN1; SMN2BACE1 | |
| SCHEMBL9799271 | 0.78 | MEN1 (0.48) | MAPTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |