Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799279 | 1.00 | MAPT (0.54) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9798856 | 0.89 | MAPT (0.58) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9798850 | 0.89 | MAPT (0.58) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2333062 | 0.84 | HTT (0.61) | MAPTL3MBTL1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9798449 | 0.81 | MAPT (0.51) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9798425 | 0.81 | MAPT (0.51) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9798455 | 0.81 | MAPT (0.51) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9798431 | 0.81 | MAPT (0.51) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9798354 | 0.80 | MAPT (0.49) | MAPTL3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL9798723 | 0.79 | TDP1 (0.43) | MAPTL3MBTL1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |