Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798449 | 1.00 | MAPT (0.51) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9798431 | 1.00 | MAPT (0.51) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9798425 | 1.00 | MAPT (0.51) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9798850 | 0.86 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9798856 | 0.86 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9798778 | 0.85 | ALDH1A1 (0.41) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9814874 | 0.83 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9798975 | 0.81 | MAPT (0.46) | MAPTLMNAPOLBALDH1A1KDM4E | |
| SCHEMBL9799286 | 0.81 | MAPT (0.54) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9799279 | 0.81 | MAPT (0.54) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423268-A1 | BRANCHED, DIPOLAR-ORIENTED POLYMER MATERIALS | MERCK PATENT GmbH (DE) | 1991-04-24 | — | — | EP | disclosed |
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990012831-A1 | BRANCHED, DIPOLAR-ORIENTED POLYMER MATERIALS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-11-01 | — | — | WO | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |