SCHEMBL9799333

SCHEMBL9799333

Nc1cccc(CCCc2cccc(Cl)c2)c1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.60
ALDH1A1 P00352 1/20 0.59
MAOA P21397 2/20 0.57
MAOB P27338 2/20 0.57
HTR3E A5X5Y0 2/20 0.56
HTR3B O95264 2/20 0.56
HTR3A P46098 2/20 0.56
HTR3D Q70Z44 2/20 0.56
HTR3C Q8WXA8 2/20 0.56
CYP19A1 P11511 1/20 0.55
PNMT P11086 2/20 0.53
AOC3 Q16853 1/20 0.51
BACE1 P56817 1/20 0.49
CYP3A4 P08684 2/20 0.48
IDO1 P14902 2/20 0.48
AGXT P21549 2/20 0.48
SIGMAR1 Q99720 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437072 0.88 MAOB (0.71) ALDH1A1MAOAMAOBCYP19A1CYP3A4
SCHEMBL1026806 0.88 MAOB (0.71) ALDH1A1MAOAMAOBCYP19A1CYP3A4
SCHEMBL5241228 0.88 TAAR1 (0.68) TAAR1HTR3EHTR3BHTR3AHTR3D
SCHEMBL9799248 0.87 CYP19A1 (0.63) TAAR1ALDH1A1MAOAMAOBHTR3E
SCHEMBL29436975 0.83 MAOB (0.71) MAOAMAOBCYP19A1CYP3A4SIGMAR1
SCHEMBL18045550 0.83 MAOB (0.71) MAOAMAOBCYP19A1CYP3A4SIGMAR1
SCHEMBL9798986 0.82 MAOB (0.83) MAOAMAOBCYP19A1IDO1SIGMAR1
SCHEMBL9799134 0.81 CYP19A1 (0.56) TAAR1MAOAMAOBCYP19A1PNMT
SCHEMBL31567921 0.81 TAAR1 (0.65) TAAR1HTR3EHTR3BHTR3AHTR3D
SCHEMBL30637158 0.81 MAOB (0.68) MAOAMAOBCYP19A1CYP3A4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5015762-A Alkoxy substituted ureas as herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
EP-0041145-B1 ARALKYL-PHENYL UREAS AND THEIR HERBICIDAL COMPOSITIONS BASF Aktiengesellschaft (DE) 1984-12-19 EP disclosed
US-4422871-A Aralkylphenylureas and herbicides containing these BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
US-4405358-A Aralkylaniline derivatives, and herbicides which contain these compounds BASF AKTIENGESELLSCHAFT (DE) 1983-09-20 US disclosed
EP-0041613-A1 Derivatives of aralkylaniline and herbicides containing these compounds BASF Aktiengesellschaft (DE) 1981-12-16 EP disclosed
EP-0041145-A2 Aralkyl-phenyl ureas and their herbicidal compositions BASF Aktiengesellschaft (DE) 1981-12-09 EP disclosed