SCHEMBL9799134

SCHEMBL9799134

Nc1cccc(CCCc2ccc(Cl)c(Cl)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.56
MAOA P21397 2/20 0.53
MAOB P27338 2/20 0.53
PNMT P11086 2/20 0.53
TAAR1 Q96RJ0 1/20 0.53
IGF1R P08069 1/20 0.50
ALOX15 P16050 1/20 0.50
SIGMAR1 Q99720 6/20 0.49
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
IDO1 P14902 2/20 0.43
TRPV1 Q8NER1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437072 0.84 MAOB (0.71) CYP19A1MAOAMAOBSIGMAR1CYP3A4
SCHEMBL1026806 0.84 MAOB (0.71) CYP19A1MAOAMAOBSIGMAR1CYP3A4
SCHEMBL9799248 0.84 CYP19A1 (0.63) CYP19A1MAOAMAOBTAAR1IGF1R
SCHEMBL6481869 0.83 PNMT (0.64) CYP19A1MAOAMAOBPNMTTAAR1
SCHEMBL9799333 0.81 TAAR1 (0.60) CYP19A1MAOAMAOBPNMTTAAR1
SCHEMBL3566361 0.81 SIGMAR1 (0.66) MAOBPNMTTAAR1IGF1RALOX15
SCHEMBL841378 0.81 CYP19A1 (0.84) CYP19A1MAOAMAOBSIGMAR1CYP3A4
SCHEMBL18045550 0.80 MAOB (0.71) CYP19A1MAOAMAOBSIGMAR1CYP3A4
SCHEMBL29436975 0.80 MAOB (0.71) CYP19A1MAOAMAOBSIGMAR1CYP3A4
SCHEMBL6475856 0.79 PNMT (0.64) CYP19A1MAOAMAOBPNMTTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5015762-A Alkoxy substituted ureas as herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
US-4422871-A Aralkylphenylureas and herbicides containing these BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0041145-A2 Aralkyl-phenyl ureas and their herbicidal compositions BASF Aktiengesellschaft (DE) 1981-12-09 EP disclosed