SCHEMBL9799394

SCHEMBL9799394

FC(F)(CCl)Oc1cc[c]cc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1067532 0.81
SCHEMBL17133820 0.79 TSHR (0.31) TSHR
SCHEMBL3426885 0.79
SCHEMBL9799586 0.79
SCHEMBL17134014 0.78
SCHEMBL9530245 0.77
SCHEMBL17134254 0.76
SCHEMBL12274650 0.76
SCHEMBL9530633 0.76 MEN1 (0.30) TSHR
SCHEMBL7463615 0.76 ALDH1A1 (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1044661-C Pesticides, insecticides, miticides and nematocides compositions containing new silanes derivatives HOECHST AG (DE) 1999-08-18 CN disclosed
CN-1032005-C Novel silane derivatives, formulations containing them and their use as pesticides HOECHST AG (DE) 1996-06-12 CN disclosed
CN-1025501-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1077588-A The agricultural chemicals, insecticide, the acaricidal nematicidal agent composition that contain novel silane derivs HOECHST AG (DE) 1993-10-27 CN disclosed
CN-1050878-A Novel silane derivs contains the preparation of this derivative and as the application of agricultural chemicals HOECHST AG (DE) 1991-04-24 CN disclosed
US-4990621-A Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
EP-0224024-B1 SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-20 EP disclosed
US-4864027-A INSECTICIDES, NEMATOCIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
US-4814340-A 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1989-03-21 US disclosed
CN-86107292-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1987-07-29 CN disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed
US-4661501-A Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1987-04-28 US disclosed