Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.69 |
| ▸ | SHBG | P04278 | 2/20 | 0.60 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 4/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841813 | 1.00 | AR (0.69) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24102603 | 0.87 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6241583 | 0.87 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24102607 | 0.87 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6836662 | 0.87 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6841921 | 0.87 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL5026470 | 0.86 | AR (0.72) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL16875673 | 0.86 | AR (0.72) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL17302821 | 0.86 | AR (0.72) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6836638 | 0.85 | AR (0.71) | ARSHBGSERPINA6SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262201-B1 | PROCESS FOR PRODUCING 7$g(a)-PROPYLSTEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |