Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.71 |
| ▸ | SHBG | P04278 | 2/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 6/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706417 | 1.00 | AR (0.71) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24102607 | 0.91 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6836662 | 0.91 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24102603 | 0.91 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6241583 | 0.91 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6841921 | 0.91 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL16875673 | 0.90 | AR (0.72) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL4259619 | 0.89 | AR (0.67) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6905409 | 0.89 | AR (0.67) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL13397457 | 0.88 | AR (0.57) | ARSHBGSERPINA6SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262201-B1 | PROCESS FOR PRODUCING 7$g(a)-PROPYLSTEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | claimed |
| US-20040209853-A1 | Orally active 7.alpha.-alkyl androgens | AKZO NOBEL N.V. (NL) | 2004-10-21 | — | — | US | disclosed |
| US-6756366-B1 | 19-NORTESTOSTERONE DERIVATIVES; ORALLY ACTIVE; HIGH POTENCY | AKZO NOBEL N.V. (NL) | 2004-06-29 | — | — | US | disclosed |
| EP-1212345-B1 | ORALLY ACTIVE 7-ALPHA-ALKYL ANDROGENS | AKZO NOBEL NV (NL) | 2003-08-06 | — | — | EP | disclosed |
| EP-0262201-B1 | PROCESS FOR PRODUCING 7$g(a)-PROPYLSTEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209853-A1 | Orally active 7.alpha.-alkyl androgens | NR5A1, AR, SHBG | AR 2/4885SHBG 3/4885SERPINA6 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.