Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663515 | 1.00 | LMNA (0.35) | LMNASLC6A2SLC6A4BLMSLC6A3 | |
| SCHEMBL45157 | 0.75 | — | — | |
| SCHEMBL38691 | 0.74 | — | — | |
| SCHEMBL16703910 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL10868262 | 0.73 | — | — | |
| SCHEMBL30514102 | 0.73 | TSHR (0.37) | LMNASLC6A2SLC6A4BLMSLC6A3 | |
| SCHEMBL1395453 | 0.72 | LMNA (0.38) | LMNATSHR | |
| SCHEMBL3087277 | 0.71 | LMNA (0.33) | LMNATSHR | |
| SCHEMBL1644502 | 0.70 | GRIK1 (0.31) | LMNA | |
| SCHEMBL1644506 | 0.70 | GRIK1 (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0140828-B1 | CROSS-LINKED POROUS POLYMERS FOR CONTROLLED DRUG RELEASE | CIBA-GEIGY AG (CH) | 1991-02-27 | — | — | EP | disclosed |
| US-4788055-A | Resinate sustained release dextromethorphan composition | CIBA-GEIGY CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4548990-A | HIGH DEGREE OF SWELLING IN ORGANIC SOLVENTS | CIBA-GEIGY CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0140828-A2 | Cross-linked porous polymers for controlled drug release | CIBA-GEIGY AG (CH) | 1985-05-08 | — | — | EP | disclosed |
| EP-0019584-A2 | Oligomers with perfluor alkyl end groups that contain mercapto groups, process for their preparation and their use as suface-active substances and as additives in fire-extinguishing compositions | CIBA-GEIGY AG (CH) | 1980-11-26 | — | — | EP | disclosed |