Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Di(Hydroxyethyl)Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethylene Glycol SCHEMBL9799381 | 0.96 | MEN1 (0.85) | — | |
| Tetraethylene Glycol SCHEMBL9799385 | 0.96 | MEN1 (0.85) | — | |
| Di(Hydroxyethyl)Ether SCHEMBL27983383 | 0.92 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL28141974 | 0.92 | TSHR (0.83) | — | |
| Di(Hydroxyethyl)Ether SCHEMBL7458751 | 0.92 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL2410410 | 0.91 | TSHR (1.00) | — | |
| Di(Hydroxyethyl)Ether SCHEMBL1462 | 0.91 | — | — | |
| Triethylene Glycol SCHEMBL28966005 | 0.88 | MEN1 (0.85) | — | |
| Triethylene Glycol SCHEMBL28790787 | 0.88 | MEN1 (0.85) | — | |
| Tetraethylene Glycol SCHEMBL8733812 | 0.88 | MEN1 (0.85) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011739-A | Moisture stable biasable transfer members and method for making same | EASTMAN KODAK COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0421299-A2 | Moisture stable biasable transfer members and method for making same | EASTMAN KODAK COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |