SCHEMBL9799610

SCHEMBL9799610

CC#CCOc1ccc(C#Cc2ccc(CCC)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACACB O00763 10/20 0.45
ADAM17 P78536 4/20 0.42
MMP2 P08253 2/20 0.40
MMP8 P22894 2/20 0.40
MMP13 P45452 2/20 0.40
MMP9 P14780 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MMP7 P09237 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16845306 0.93 ADAM17 (0.46) ADAM17MMP2MMP8MMP13MMP9
SCHEMBL9799590 0.87 ACACB (0.45) ACACBALDH1A1
SCHEMBL8046400 0.81 ACACB (0.45) ACACB
SCHEMBL8753212 0.81 ACACB (0.60) ACACB
SCHEMBL7511204 0.81 KCNH2 (0.50) ACACB
SCHEMBL8029213 0.80 ACACB (0.44) ACACB
SCHEMBL9637432 0.80 ACACB (0.56) ACACBALDH1A1
SCHEMBL13433661 0.80 ACACB (0.64) ACACBALDH1A1
SCHEMBL9799593 0.79 NR5A1 (0.51) ADAM17MMP13MMP9ALDH1A1
SCHEMBL8275564 0.79 ADAM17 (0.49) ADAM17MMP2MMP8MMP13MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2083346-A None JP disclosed
US-5047169-A ELEVATES REFRACTIVE INDEX ANISOTROPY OF LIFQUID CRYSTAL COMPOUNDS; HIGH SPEED RESPONSE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-09-10 US disclosed
JP-H0283346-A ALKYNYLOXYTOLAN COMPOUND ADEKA ARGUS CHEM CO LTD 1990-03-23 JP disclosed