Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799838 | 0.86 | KMT2A (0.64) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9799834 | 0.86 | KMT2A (0.64) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7821134 | 0.85 | MAPT (0.71) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| Nitrobenzene SCHEMBL27471209 | 0.82 | TSHR (0.67) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL27707208 | 0.80 | TSHR (0.59) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL12189436 | 0.78 | MEN1 (0.64) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| Dinitrophenylene SCHEMBL27494788 | 0.77 | TSHR (0.65) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL31155741 | 0.77 | MEN1 (0.60) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2702303 | 0.77 | NPC1 (0.71) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL31155757 | 0.76 | CHRNB2 (0.69) | MEN1KMT2AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277376-B1 | AROMATIC AMIDE GROUPS-CONTAINING DIAMINES AND POLYMERS IN WHICH THESE DIAMINES ARE INCORPORATED | AKZO N.V. (NL) | 1991-02-27 | — | — | EP | disclosed |
| US-4980444-A | Polyamides, polyureas, polyimides; heat resistance, melt processability, high strength fibers, films | AKZO N.V. (NL) | 1990-12-25 | — | — | US | disclosed |
| US-4851562-A | HEAT RESISTANCE, MELT PROCESS ABILITY | AKZO N.V. (NL) | 1989-07-25 | — | — | US | disclosed |
| EP-0277376-A1 | Aromatic amide groups-containing diamines and polymers in which these diamines are incorporated | AKZO N.V. (NL) | 1988-08-10 | — | — | EP | disclosed |