Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | DDX3X | O00571 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ULK1 | O75385 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15886741 | 0.87 | PTGS1 (0.59) | PTGS1DDX3XALDH1A1MEN1KMT2A | |
| SCHEMBL308208 | 0.86 | PTGS1 (0.72) | PTGS1DDX3XALDH1A1CNR1SMN1; SMN2 | |
| SCHEMBL31171978 | 0.86 | PTGS1 (0.72) | PTGS1DDX3XALDH1A1CNR1SMN1; SMN2 | |
| SCHEMBL29568967 | 0.86 | PTGS1 (0.72) | PTGS1DDX3XALDH1A1CNR1SMN1; SMN2 | |
| SCHEMBL8403932 | 0.86 | PTGS1 (0.72) | PTGS1DDX3XALDH1A1CNR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11740733 | 0.84 | PTGS1 (0.70) | PTGS1DDX3XALDH1A1CNR1SMN1; SMN2 | |
| SCHEMBL2126328 | 0.82 | PTGS1 (0.68) | PTGS1DDX3XALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1680201 | 0.82 | KCNK3 (0.50) | MEN1KMT2AKCNK3KCNK9MAPT | |
| SCHEMBL16431098 | 0.82 | PTGS1 (0.63) | PTGS1DDX3XALDH1A1CNR1SMN1; SMN2 | |
| SCHEMBL7379264 | 0.81 | KCNK3 (0.71) | ALDH1A1MEN1KMT2AKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277376-B1 | AROMATIC AMIDE GROUPS-CONTAINING DIAMINES AND POLYMERS IN WHICH THESE DIAMINES ARE INCORPORATED | AKZO N.V. (NL) | 1991-02-27 | — | — | EP | disclosed |
| EP-0277376-A1 | Aromatic amide groups-containing diamines and polymers in which these diamines are incorporated | AKZO N.V. (NL) | 1988-08-10 | — | — | EP | disclosed |