Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246164 | 1.00 | TDP1 (0.52) | TDP1L3MBTL1KCNH2HRH3TBXAS1 | |
| SCHEMBL9245810 | 0.96 | TP53 (0.53) | TDP1L3MBTL1TSHRLMNASMN1; SMN2 | |
| SCHEMBL9245818 | 0.96 | TP53 (0.53) | TDP1L3MBTL1TSHRLMNASMN1; SMN2 | |
| SCHEMBL9244776 | 0.89 | L3MBTL1 (0.47) | TDP1L3MBTL1KCNH2HRH3TBXAS1 | |
| SCHEMBL9244773 | 0.89 | L3MBTL1 (0.47) | TDP1L3MBTL1KCNH2HRH3TBXAS1 | |
| SCHEMBL11854557 | 0.87 | ESR1 (0.52) | L3MBTL1KMT2AABCG2TSHRESR1 | |
| SCHEMBL5166263 | 0.86 | TDP1 (0.66) | TDP1L3MBTL1KCNH2HRH3TBXAS1 | |
| SCHEMBL9799848 | 0.85 | MAPT (0.59) | L3MBTL1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL9241494 | 0.85 | MAPT (0.59) | L3MBTL1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL9245384 | 0.85 | HPGD (0.45) | TDP1L3MBTL1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068252-A | Acids, esters, amides, alcohol and ether derivatives | ALLERGAN, INC. (US) | 1991-11-26 | — | — | US | disclosed |