SCHEMBL9799786

SCHEMBL9799786

BrSc1nc2ccccc2s1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
HSD17B10 Q99714 5/20 0.73
HPGD P15428 5/20 0.73
FBP1 P09467 3/20 0.73
ALOX15 P16050 3/20 0.73
TDP1 Q9NUW8 2/20 0.73
ADRA2A P08913 1/20 0.73
ADORA3 P0DMS8 1/20 0.73
DRD2 P14416 1/20 0.73
ADRA2B P18089 1/20 0.73
ADRA2C P18825 1/20 0.73
DRD1 P21728 1/20 0.73
MC5R P33032 1/20 0.73
OPRM1 P35372 1/20 0.73
DRD3 P35462 1/20 0.73
OPRK1 P41145 1/20 0.73
CCR2 P41597 1/20 0.73
HTR6 P50406 1/20 0.73
SLC6A3 Q01959 1/20 0.73
PDK1 Q15118 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzothiazyl Disulfide SCHEMBL11095350 0.84 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL381557 0.84 ALDH1A1 (0.76) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL30005981 0.84 ALDH1A1 (0.76) ALDH1A1HSD17B10HPGDFBP1ALOX15
Benzothiazyl Disulfide SCHEMBL23527 0.84 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDFBP1ALOX15
Benzothiazyl Disulfide SCHEMBL29356396 0.84 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDFBP1ALOX15
Benzothiazyl Disulfide SCHEMBL8609896 0.83 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDFBP1ALOX15
Benzothiazyl Disulfide SCHEMBL3787918 0.83 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL5466260 0.82 ALDH1A1 (0.66) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL10362146 0.81 ALDH1A1 (0.70) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL19229969 0.81 ALDH1A1 (0.70) ALDH1A1HSD17B10HPGDFBP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5045221-A corrosion resistance; additive to extreme pressure, temperature lubricants ISTITUT FRANCAIS DU PETROLE (FR) 1991-09-03 US disclosed
US-4931555-A CEPHALOSPORINS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-06-05 US disclosed
EP-0159936-B1 PROCESS FOR THE PREPARATION OF POLYSULFURISED OLEFINS, PRODUCTS SO OBTAINED AND THEIR USE AS ADDITIVES FOR LUBRICANTS Institut Français du Pétrole (FR) 1987-06-24 EP disclosed
US-4435321-A BACTERICIDES AND INTERMEDIATES FOR 2- OR 3-CEPHEMS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-03-06 US disclosed
US-4410458-A GROUP 5B OR 6B METAL COMPOUND OXIDATION CATALYST FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-10-18 US disclosed
US-4267340-A BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-12 US disclosed
US-4071527-A Certain benzothiazole compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-01-31 US disclosed
US-4036847-A ANTIBACTERIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-07-19 US disclosed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US disclosed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US disclosed