Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | MGAM | O43451 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SI | P14410 | 3/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800102 | 0.81 | TDP1 (0.42) | L3MBTL1TSHRTDP1MAPTPPARD | |
| SCHEMBL9240945 | 0.79 | HPGD (0.45) | L3MBTL1TDP1MAPTPPARDPPARA | |
| SCHEMBL9245384 | 0.79 | HPGD (0.45) | L3MBTL1TDP1MAPTPPARDPPARA | |
| SCHEMBL9799811 | 0.79 | HPGD (0.45) | L3MBTL1TDP1MAPTPPARDPPARA | |
| SCHEMBL384028 | 0.78 | CA12 (0.53) | L3MBTL1TDP1MAPTALDH1A1HSD17B10 | |
| SCHEMBL9243719 | 0.76 | TSHR (0.45) | L3MBTL1TSHRTDP1MAPTPPARD | |
| SCHEMBL9243610 | 0.75 | TDP1 (0.46) | L3MBTL1TDP1MAPTPPARDPPARA | |
| SCHEMBL8458466 | 0.73 | PPARG (0.49) | L3MBTL1TDP1MAPTPPARGALDH1A1 | |
| SCHEMBL8458464 | 0.73 | PPARG (0.49) | L3MBTL1TDP1MAPTPPARGALDH1A1 | |
| SCHEMBL9799788 | 0.72 | MAOB (0.46) | L3MBTL1TDP1MAPTPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068252-A | Acids, esters, amides, alcohol and ether derivatives | ALLERGAN, INC. (US) | 1991-11-26 | — | — | US | disclosed |
| US-4992468-A | Treatment of skin disorders | ALLERGAN, INC. (US) | 1991-02-12 | — | — | US | disclosed |