Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799811 | 0.81 | HPGD (0.45) | LMNAKDM4ETDP1HTTPPARD | |
| SCHEMBL9240945 | 0.81 | HPGD (0.45) | LMNAKDM4ETDP1HTTPPARD | |
| SCHEMBL9245384 | 0.81 | HPGD (0.45) | LMNAKDM4ETDP1HTTPPARD | |
| SCHEMBL384028 | 0.80 | CA12 (0.53) | LMNATDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9243610 | 0.79 | TDP1 (0.46) | SMN1; SMN2TDP1NPC1PPARDPPARA | |
| SCHEMBL9799788 | 0.78 | MAOB (0.46) | LMNASMN1; SMN2KDM4ETDP1PPARD | |
| SCHEMBL9800102 | 0.78 | TDP1 (0.42) | TSHRLMNASMN1; SMN2TDP1NPC1 | |
| SCHEMBL27471314 | 0.77 | TSHR (0.65) | TSHRMAPK10LMNAKDM4ETDP1 | |
| SCHEMBL9799846 | 0.76 | L3MBTL1 (0.41) | TSHRTDP1GAAPPARDPPARA | |
| SCHEMBL8458466 | 0.74 | PPARG (0.49) | LMNATDP1PPARGL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410742-B1 | Phenylethenyl compounds having retinoid-like activity | ALLERGAN INC (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0647248-A1 | SURFACTANTS DERIVED FROM POLYOXYALKYLENES AND SUBSTITUTED SUCCINIC ANHYDRIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-04-12 | — | — | EP | disclosed |
| WO-1994000508-A1 | SURFACTANTS DERIVED FROM POLYOXYALKYLENES AND SUBSTITUTED SUCCINIC ANHYDRIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-06 | — | — | WO | disclosed |