Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765606 | 0.93 | ITGB2 (0.36) | PYGLLMNATDP1PLGPDE5A | |
| SCHEMBL9765542 | 0.93 | ITGB2 (0.36) | PYGLLMNATDP1PLGPDE5A | |
| SCHEMBL9765599 | 0.92 | LMNA (0.36) | LMNATDP1PLGPDE5ARORC | |
| SCHEMBL9765596 | 0.92 | LMNA (0.36) | LMNATDP1PLGPDE5ARORC | |
| SCHEMBL9765550 | 0.91 | POLB (0.40) | PYGLLMNATDP1GAAPKLR | |
| SCHEMBL9765570 | 0.91 | POLB (0.40) | PYGLLMNATDP1GAAPKLR | |
| SCHEMBL195323 | 0.91 | POLB (0.40) | PYGLLMNATDP1GAAPKLR | |
| SCHEMBL9765574 | 0.91 | POLB (0.40) | PYGLLMNATDP1GAAPKLR | |
| SCHEMBL9765547 | 0.91 | POLB (0.40) | PYGLLMNATDP1GAAPKLR | |
| SCHEMBL9765587 | 0.91 | POLB (0.40) | PYGLLMNATDP1GAAPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231619-B1 | 3-PHENOXY(OR PHENYLTHIO)CYCLOPENTANECARBONYLAMINO ACID ANALOGUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | claimed |