Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL979997 | 0.87 | KDM4E (0.44) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| SCHEMBL978176 | 0.86 | KDM4E (0.43) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| SCHEMBL15623160 | 0.84 | KDM4E (0.49) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| Hydrochloric Acid SCHEMBL980211 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL978175 | 0.71 | KDM4E (0.42) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| SCHEMBL978042 | 0.70 | KDM4E (0.46) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| Iodide SCHEMBL979604 | 0.70 | KDM4E (0.45) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| SCHEMBL979954 | 0.69 | KDM4E (0.42) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| SCHEMBL12923308 | 0.69 | KDM4E (0.48) | ALDH1A1KDM4ELMNAL3MBTL1CHRNA4 | |
| SCHEMBL980208 | 0.66 | SLC6A9 (0.35) | ALDH1A1TSHRPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680282-B2 | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2014-03-25 | — | — | US | disclosed |
| US-20110015174-A1 | CYCLIC INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015174-A1 | CYCLIC INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | ALDH1A1 196/4885KDM4E 1974/4885LMNA 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.