Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598925 | 0.93 | ALDH1A1 (0.43) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL9181189 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL10595487 | 0.82 | MEN1 (0.44) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL9174275 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL10598629 | 0.82 | PPARA (0.46) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL10598806 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL9256223 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL11114226 | 0.79 | POLB (0.55) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL9178355 | 0.78 | HPGD (0.50) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL9799955 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HPGDPOLBSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0128862-B1 | ANTI-CORROSIVE COATING COMPOSITION | CIBA-GEIGY AG (CH) | 1989-03-01 | — | — | EP | disclosed |
| EP-0183647-B1 | ANTI-CORROSIVE AQUEOUS PAINTS | CIBA-GEIGY AG (CH) | 1989-02-15 | — | — | EP | disclosed |
| EP-0128862-A2 | Anti-corrosive coating composition | CIBA-GEIGY AG (CH) | 1984-12-19 | — | — | EP | disclosed |