Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | SDHA | P31040 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CALML3 | P27482 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831990 | 1.00 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6212217 | 0.93 | MAOA (0.53) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6212220 | 0.93 | MAOA (0.53) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9175963 | 0.92 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5141633 | 0.86 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6208847 | 0.86 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6240071 | 0.86 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6240078 | 0.86 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6364832 | 0.86 | MAOA (0.54) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6364834 | 0.86 | MAOA (0.54) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036093-A | Effective against grampositive bacteria including some antibiotic resistant strains | DU PONT MERCK PHARMACEUTICAL (US) | 1991-07-30 | — | — | US | disclosed |
| US-5036092-A | Effective against antibiotic resistant streptococci and staphylococci | DU PONT MERCK PHARMACEUTICAL (US) | 1991-07-30 | — | — | US | disclosed |