Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447067 | 0.89 | AR (0.64) | ARCYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL9447007 | 0.79 | CYSLTR1 (0.54) | ARCYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL9447118 | 0.78 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2GPBAR1NPC1LMNA | |
| SCHEMBL9447043 | 0.77 | AR (0.50) | ARCYSLTR1CYSLTR2GPBAR1NPC1 | |
| SCHEMBL5385220 | 0.76 | NPC1 (0.70) | ARNPC1RAB9ACA12CA1 | |
| SCHEMBL9446959 | 0.74 | AR (0.52) | ARNPC1RAB9ALMNAHPGD | |
| SCHEMBL9446978 | 0.74 | CYSLTR1 (0.49) | ARCYSLTR1CYSLTR2GPBAR1NPC1 | |
| SCHEMBL10544630 | 0.74 | CYSLTR1 (0.84) | CYSLTR1CYSLTR2GPBAR1LMNAHPGD | |
| SCHEMBL9447014 | 0.73 | CYSLTR1 (0.44) | ARCYSLTR1CYSLTR2GPBAR1LMNA | |
| SCHEMBL11431936 | 0.72 | NPC1 (0.64) | ARNPC1RAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |