Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431936 | 0.93 | NPC1 (0.64) | NPC1RAB9AARCA12CA1 | |
| SCHEMBL3563414 | 0.84 | AR (0.62) | NPC1RAB9AARCA12CA1 | |
| SCHEMBL7263640 | 0.81 | NPC1 (0.74) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL5385213 | 0.80 | AR (0.54) | NPC1RAB9AARCA12CA1 | |
| SCHEMBL25788194 | 0.79 | NPC1 (0.67) | NPC1RAB9ALMNASMN1; SMN2NR5A1 | |
| SCHEMBL14113144 | 0.79 | NPC1 (0.93) | NPC1RAB9AARCA12CA1 | |
| SCHEMBL11431934 | 0.78 | AR (0.52) | NPC1RAB9AARCA12CA1 | |
| SCHEMBL3555020 | 0.78 | AR (0.61) | NPC1RAB9AARCA12CA1 | |
| SCHEMBL27812662 | 0.78 | AR (0.71) | NPC1RAB9AARLMNAHPGD | |
| SCHEMBL13763467 | 0.78 | HPGD (0.56) | NPC1RAB9AARCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312337-B2 | Oxadiazoles and their manufacture | EASTMAN KODAK COMPANY (US) | 2007-12-25 | — | — | US | claimed |
| US-7268235-B2 | Method for preparation of N-pyrazolylamidoximes | EASTMAN KODAK COMPANY (US) | 2007-09-11 | — | — | US | claimed |
| US-20060074245-A1 | Method for preparation of N-pyrazolylamidoximes | EASTMAN KODAK COMPANY | 2006-04-06 | — | — | US | claimed |
| US-20060069262-A1 | Oxadiazoles and their manufacture | EASTMAN KODAK COMPANY | 2006-03-30 | — | — | US | claimed |
| US-6657083-B2 | Photographic couplers; acylation amine group in position 2 | EASTMAN KODAK COMPANY | 2003-12-02 | — | — | US | claimed |
| US-6613943-B2 | Intermediates for 4-substituted-2,5-diaminophenol derivatives as phenolic cyan couplers for color photography; deblocking the 2-acyl group by hydrolysis | EASTMAN KODAK COMPANY | 2003-09-02 | — | — | US | claimed |
| US-20030109716-A1 | 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM | EASTMAN KODAK COMPANY | 2003-06-12 | — | — | US | claimed |
| US-20030109753-A1 | 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them | EASTMAN KODAK COMPANY | 2003-06-12 | — | — | US | claimed |
| US-6525219-B1 | Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation | EASTMAN KODAK COMPANY | 2003-02-25 | — | — | US | claimed |
| US-6476202-B1 | 5-acylamino-2-arylazo, nitro, or nitroso-4-substituted-phenol compounds and method of using them | EASTMAN KODAK COMPANY | 2002-11-05 | — | — | US | claimed |
| US-4840883-A | STORAGE STABILITY | KONICA CORPORATION (JP) | 1989-06-20 | — | — | US | claimed |
| EP-0296780-A2 | Light-sensitive silver halide color photographic material containing novel cyan coupler | KONICA CORPORATION (JP) | 1988-12-28 | — | — | EP | claimed |
| US-7312337-B2 | Oxadiazoles and their manufacture | EASTMAN KODAK COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7268235-B2 | Method for preparation of N-pyrazolylamidoximes | EASTMAN KODAK COMPANY (US) | 2007-09-11 | — | — | US | disclosed |
| US-20060074245-A1 | Method for preparation of N-pyrazolylamidoximes | EASTMAN KODAK COMPANY | 2006-04-06 | — | — | US | disclosed |
| US-20060069262-A1 | Oxadiazoles and their manufacture | EASTMAN KODAK COMPANY | 2006-03-30 | — | — | US | disclosed |
| US-6525219-B1 | Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation | EASTMAN KODAK COMPANY | 2003-02-25 | — | — | US | disclosed |
| US-6482953-B1 | 2-benzyloxy-4-nitro-5-substituted-acylanilide compounds and method of using them | EASTMAN KODAK COMPANY | 2002-11-19 | — | — | US | disclosed |
| US-6482985-B1 | 2-benzyloxy-5-halo-acylanilide compounds and method of using them | EASTMAN KODAK COMPANY | 2002-11-19 | — | — | US | disclosed |
| US-4840883-A | STORAGE STABILITY | KONICA CORPORATION (JP) | 1989-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109753-A1 | 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them | CBR3, AADAC, HAAO | NPC1 2847/4885RAB9A 1906/4885AR 234/4885 |
| US-20030109716-A1 | 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM | AADAT, AAAS, ANXA7 | NPC1 4256/4885RAB9A 1371/4885AR 183/4885 |
| US-20060069262-A1 | Oxadiazoles and their manufacture | OXA1L, CYP1B1, OXER1 | NPC1 3914/4885RAB9A 4154/4885AR 889/4885 |
| US-20060074245-A1 | Method for preparation of N-pyrazolylamidoximes | KCNH1, KCNJ2, KCNH2 | NPC1 3178/4885RAB9A 3696/4885AR 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.