Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800724 | 0.88 | FOLH1 (0.49) | TGFBR1MME | |
| SCHEMBL9800723 | 0.88 | FOLH1 (0.49) | TGFBR1MME | |
| SCHEMBL2920459 | 0.84 | KMT2A (0.47) | TGFBR1CA2CA1KMT2AMMP2 | |
| SCHEMBL7046561 | 0.84 | KMT2A (0.47) | TGFBR1CA2CA1KMT2AMMP2 | |
| SCHEMBL31289501 | 0.80 | KMT2A (0.50) | TGFBR1TASP1CA2CA1KMT2A | |
| SCHEMBL9073938 | 0.79 | KMT2A (0.42) | CA2CA1KMT2AALOX15BLM | |
| SCHEMBL28155914 | 0.79 | KMT2A (0.42) | CA2CA1KMT2AALOX15BLM | |
| SCHEMBL30903444 | 0.79 | TGFBR1 (0.45) | TGFBR1TASP1CA2CA1KMT2A | |
| SCHEMBL30933103 | 0.79 | TGFBR1 (0.45) | TGFBR1TASP1CA2CA1KMT2A | |
| SCHEMBL10804027 | 0.78 | FNTA (0.45) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017690-A | Deblocking N-formyl aspartame compounds | W. R. GRACE & CO.-CONN. (US) | 1991-05-21 | — | — | US | disclosed |