SCHEMBL9800896

SCHEMBL9800896

CCCCCCCC/C=C\CCCCCCCCNC(=O)Nc1c(CC)cccc1C(C)C

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.49
EPHX2 P34913 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9800897 1.00 EPHX1 (0.49) EPHX1EPHX2
SCHEMBL9800919 0.93 EPHX1 (0.55) EPHX1
SCHEMBL9800917 0.93 EPHX1 (0.55) EPHX1
SCHEMBL9800949 0.90
SCHEMBL9800934 0.90 EPHX2 (0.55) EPHX1EPHX2
SCHEMBL9800932 0.90 EPHX2 (0.55) EPHX1EPHX2
SCHEMBL9800920 0.86
SCHEMBL9800911 0.86
SCHEMBL9800905 0.82 EPHX1 (0.63) EPHX1EPHX2
SCHEMBL9800922 0.82 EPHX1 (0.63) EPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297610-B1 N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase WARNER-LAMBERT COMPANY (US) 1991-03-13 EP disclosed
EP-0297610-A1 N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase WARNER-LAMBERT COMPANY (US) 1989-01-04 EP disclosed