Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | FDPS | P14324 | 9/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819694 | 1.00 | GGPS1 (0.38) | GGPS1FDPSSMPD1CES2LPAR1 | |
| SCHEMBL11040924 | 1.00 | GGPS1 (0.38) | GGPS1FDPSSMPD1CES2LPAR1 | |
| SCHEMBL9123282 | 1.00 | GGPS1 (0.38) | GGPS1FDPSSMPD1CES2LPAR1 | |
| SCHEMBL11280542 | 1.00 | GGPS1 (0.38) | GGPS1FDPSSMPD1CES2LPAR1 | |
| SCHEMBL4084299 | 0.98 | FDPS (0.34) | GGPS1FDPSSMPD1CES2LPAR1 | |
| SCHEMBL11043523 | 0.91 | FDPS (0.31) | FDPS | |
| SCHEMBL9322915 | 0.91 | FFAR1 (0.31) | — | |
| SCHEMBL10840235 | 0.91 | FFAR1 (0.31) | — | |
| SCHEMBL192803 | 0.89 | — | — | |
| SCHEMBL8763158 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297610-B1 | N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase | WARNER-LAMBERT COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0297610-A1 | N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase | WARNER-LAMBERT COMPANY (US) | 1989-01-04 | — | — | EP | disclosed |