Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260864 | 0.86 | CYP1A2 (0.47) | CYP1A2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL29368452 | 0.86 | CYP1A2 (0.47) | CYP1A2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL7755626 | 0.83 | TDP1 (0.52) | ERN1TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL5748776 | 0.81 | PTPRC (0.42) | CYP1A2ERN1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL2236124 | 0.81 | CYP1A2 (0.41) | CYP1A2ERN1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL28218218 | 0.81 | POLB (0.52) | CYP1A2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL18331626 | 0.79 | CYP1A2 (0.42) | CYP1A2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL10033263 | 0.79 | CYP1A2 (0.58) | CYP1A2ERN1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL14894155 | 0.78 | ALDH1A1 (0.56) | CYP1A2ERN1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL1640597 | 0.78 | ALDH1A1 (0.49) | CYP1A2ERN1TDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185762-B1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0185762-A4 | CELL-DELIVERY AGENT. | DANA FARBER CANCER INST INC (US) | 1986-12-01 | — | — | EP | disclosed |
| US-4625014-A | Cell-delivery agent | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0185762-A1 | CELL-DELIVERY AGENT. | DANA FARBER CANCER INST INC (US) | 1986-07-02 | — | — | EP | disclosed |
| WO-1986000527-A1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-01-30 | — | — | WO | disclosed |