Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TPI1 | P60174 | 1/20 | 0.37 |
| ▸ | SAT1 | P21673 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637889 | 0.98 | — | — | |
| Magnesium SCHEMBL9802275 | 0.95 | LPAR3 (0.45) | LPAR3LPAR2LPAR1ENPP2TPI1 | |
| SCHEMBL17754006 | 0.84 | LPAR3 (0.54) | LPAR3LPAR2LPAR1ENPP2TPI1 | |
| SCHEMBL2734614 | 0.81 | — | — | |
| SCHEMBL10599366 | 0.80 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ENPP2S1PR2 | |
| SCHEMBL10240866 | 0.77 | PLA2G2A (0.37) | SAT1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL17859165 | 0.77 | LPAR3 (0.44) | LPAR3LPAR2LPAR1ENPP2TPI1 | |
| SCHEMBL13431174 | 0.76 | PPARD (0.42) | LPAR3LPAR2LPAR1SAT1S1PR2 | |
| SCHEMBL17758486 | 0.76 | LPAR2 (0.45) | LPAR3LPAR2LPAR1ENPP2TPI1 | |
| SCHEMBL13941965 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068228-A | Nervous system disorders | KOEHLER GERNOT (DE) | 1991-11-26 | — | — | US | disclosed |