Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 4/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.69 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | MAOB | P27338 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavanone SCHEMBL29678059 | 1.00 | TP53 (1.00) | TP53KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL31238423 | 0.87 | KDM4E (0.76) | TP53KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL3515838 | 0.87 | HPGD (0.77) | TP53KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL31552891 | 0.87 | HPGD (0.77) | TP53KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL4981350 | 0.86 | MAPT (0.76) | TP53KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL31238518 | 0.85 | KDM4E (0.72) | TP53KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL25201659 | 0.84 | KDM4E (0.73) | TP53KDM4EHSD17B10MAPTHPGD | |
| Flavanone SCHEMBL5273130 | 0.84 | KDM4E (0.76) | TP53KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL4648917 | 0.84 | KDM4E (1.00) | TP53KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL25202745 | 0.84 | MAPT (0.72) | TP53KDM4EHSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230119060-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE | MEDIENCE CO., LTD. (KR) | 2023-04-20 | — | — | US | claimed |
| WO-2023064318-A1 | BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE | Natural Extraction Systems, LLC (US) | 2023-04-20 | — | — | WO | claimed |
| WO-2022255765-A1 | NOVEL FLUORINE-SUBSTITUTED FLAVONOID DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES, COMPRISING SAME | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | claimed |
| US-20220249431-A1 | ANTIMYCOTIC | Karl-Franzens-Universität Graz (AT) | 2022-08-11 | — | — | US | claimed |
| EP-4003522-A1 | ANTIMYCOTIC | Karl-Franzens-Universität Graz (AT) | 2022-06-01 | — | — | EP | claimed |
| WO-2021042001-A1 | COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES | Natural Extraction Systems, LLC (US) | 2021-03-04 | — | — | WO | claimed |
| WO-2021013931-A1 | ANTIMYCOTIC | Karl-Franzens-Universität Graz (AT) | 2021-01-28 | — | — | WO | claimed |
| EP-3769815-A1 | ANTIMYCOTIC | Karl-Franzens-Universität Graz (AT) | 2021-01-27 | — | — | EP | claimed |
| EP-3302083-A1 | MONO AND DI-GLYCERIDE ESTERS OF OMEGA-3 FATTY ACID EMULSIONS | Mycell Technologies, LLC (US) | 2018-04-11 | — | — | EP | claimed |
| CN-107645910-A | Mono-and diglycerides of omega-3 fatty acid emulsions | 麦赛尔科技有限责任公司 | 2018-01-30 | — | — | CN | claimed |
| WO-2010042728-A1 | SMALL MOLECULE MODULATORS OF PRONGF UPTAKE | CORNELL UNIVERSITY (US) | 2010-04-15 | — | — | WO | claimed |
| WO-2010038153-A1 | USE OF SOX TRANSCRIPTION FACTOR ACTI\\ATORS FOR STIMULATING CHONDROGENESIS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-04-08 | — | — | WO | claimed |
| US-20060229262-A1 | Pharmaceutical composition for treatment of infection with drug resistant bacterium and disinfectant | TOMIHIKO HIGUCHI (JP) | 2006-10-12 | — | — | US | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| WO-2005020881-A2 | COMPOSITIONS OF FLAVONOIDS AND FLAVONOID-CONTAINING EXTRACTS AND THE TREATMENT OF DISEASES | SHANGHAI COMMAN PHARMACEUTICAL CO. (US) | 2005-03-10 | — | — | WO | claimed |
| US-20050049206-A1 | Compositions of flavonoids and flavonoid-containing extracts and the treatment of diseases | SHANGHAI COMMAN PHARMACEUTICAL CO. LTD. (CN) | 2005-03-03 | — | — | US | claimed |
| US-20040229825-A1 | Pharmaceutical composition for treatment of infection with drug resistant bacterium and disinfectant | ALPS PHARMACEUTICAL IND., CO., LTD. (JP) | 2004-11-18 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220249431-A1 | ANTIMYCOTIC | ETF1, FOXM1, RIF1 | TP53 2041/4885KDM4E 1705/4885HSD17B10 3005/4885 |
| US-20230119060-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE | SLC5A2, SLC5A1, SLC5A6 | TP53 134/4885KDM4E 1490/4885HSD17B10 455/4885 |
| US-20050049206-A1 | Compositions of flavonoids and flavonoid-containing extracts and the treatment of diseases | FNTA, COLGALT1, F3 | TP53 3021/4885KDM4E 2663/4885HSD17B10 3661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.