Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.80 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | CASP1 | P29466 | 1/20 | 0.72 |
| ▸ | CASP7 | P55210 | 1/20 | 0.72 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13730323 | 0.95 | KDM4E (0.90) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| SCHEMBL31527819 | 0.89 | KDM4E (1.00) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| SCHEMBL4650049 | 0.89 | KDM4E (1.00) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| SCHEMBL28016978 | 0.88 | ALDH1A1 (0.79) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| Flavanone SCHEMBL5273130 | 0.86 | KDM4E (0.76) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| Flavanone SCHEMBL980197 | 0.84 | TP53 (1.00) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| Flavanone SCHEMBL29678059 | 0.84 | TP53 (1.00) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| SCHEMBL17786520 | 0.84 | KDM4E (0.80) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| SCHEMBL29129663 | 0.81 | CYP2C19 (0.68) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 | |
| SCHEMBL8934505 | 0.81 | CYP1A1 (0.69) | KDM4ECYP2C19HSD17B10ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| WO-2008141074-A1 | IDENTIFICATION OF COMPOUNDS THAT PROTECT AGAINST AMYLOID DISEASES | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-11-20 | — | — | WO | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| CN-101089245-A | Virtual screening method for compound pesticide effect matter base of traditional chinese medicine | INST OF RADIOACTIVE MEDICINE C (CN) | 2007-12-19 | — | — | CN | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | KDM4E 1065/4885CYP2C19 185/4885HSD17B10 1010/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | KDM4E 2309/4885CYP2C19 2389/4885HSD17B10 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.