Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802023 | 1.00 | HSD17B10 (0.53) | HSD17B10KDM4EUSP2ESR1POLB | |
| SCHEMBL9802678 | 1.00 | HSD17B10 (0.53) | HSD17B10KDM4EUSP2ESR1POLB | |
| SCHEMBL9802422 | 0.93 | HSD17B10 (0.46) | HSD17B10KDM4EUSP2ESR1POLB | |
| SCHEMBL9802465 | 0.89 | IDO1 (0.41) | HSD17B10KDM4EUSP2ESR1POLB | |
| SCHEMBL9802108 | 0.87 | ADORA2B (0.43) | HSD17B10KDM4EUSP2ESR1POLB | |
| SCHEMBL9802101 | 0.87 | ADORA2B (0.43) | HSD17B10KDM4EUSP2ESR1POLB | |
| SCHEMBL9802642 | 0.87 | ADORA2B (0.43) | HSD17B10KDM4EUSP2ESR1POLB | |
| SCHEMBL9801995 | 0.86 | IDO1 (0.47) | HSD17B10KDM4EIDO1TDO2GLA | |
| SCHEMBL4112461 | 0.83 | IDO1 (0.43) | HSD17B10KDM4EUSP2ESR1POLB | |
| SCHEMBL3347463 | 0.83 | IDO1 (0.43) | HSD17B10KDM4EUSP2ESR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |