⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205349 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL14479589 | 0.77 | — | — | |
| SCHEMBL2178952 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27506089 | 0.74 | — | — | |
| Hydrogen Sulfide SCHEMBL27537321 | 0.74 | — | — | |
| SCHEMBL28362309 | 0.74 | — | — | |
| Water SCHEMBL27783959 | 0.74 | — | — | |
| SCHEMBL1358796 | 0.74 | — | — | |
| SCHEMBL1203416 | 0.72 | — | — | |
| SCHEMBL8423099 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121290-A1 | THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.4) LIMITED (GB) | 2024-06-13 | — | — | WO | disclosed |
| WO-2023233295-A1 | THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS AND USES THEREOF | IDEAYA BIOSCIENCES, INC. (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2022150637-A1 | NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF | IMMUNEXT, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| EP-3439658-B1 | SOLUBLE C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2021-11-24 | — | — | EP | disclosed |
| EP-3906969-A1 | ANTIHYPERTENSIVE POLYOL COMPOUND AND DERIVATIVE THEREOF | East China University of Science and Technology (CN) | 2021-11-10 | — | — | EP | disclosed |
| WO-2021034373-A1 | CONJUGATES OF GUIDE RNA-CAS PROTEIN COMPLEX | ZHONG MINGHONG (US) | 2021-02-25 | — | — | WO | disclosed |
| WO-2020249117-A1 | ANTIHYPERTENSIVE POLYOL COMPOUND AND DERIVATIVE THEREOF | 华东理工大学 | 2020-12-17 | — | — | WO | disclosed |
| EP-2903971-B1 | SUBSTITUTED N-(3-(PYRIMIDIN-4-YL)PHENYL)ACRYLAMIDE ANALOGS AS TYROSINE RECEPTOR KINASE BTK INHIBITORS | UNIV UTAH RES FOUND (US) | 2019-06-12 | — | — | EP | disclosed |
| CN-106558731-A | A kind of lithium-ion battery electrolytes and lithium ion battery | 比亚迪股份有限公司 | 2017-04-05 | — | — | CN | disclosed |
| EP-3098273-A1 | DISPERSION CONTAINING METAL OXIDE PARTICLES | Nippon Shokubai Co., Ltd. (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-8342042-B2 | Device for collecting chemical compounds and related methods | BATTELLE ENERGY ALLIANCE, LLC (US) | 2013-01-01 | — | — | US | disclosed |
| US-20120225832-A1 | Amphiphilic Compositions and Methods for Preparing and Using Same | YALE UNIVERSITY (US) | 2012-09-06 | — | — | US | disclosed |
| US-8106209-B2 | Substituted aminothiazole prodrugs of compounds with anti-HCV activity | ACHILLION PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-8106209-B2 | Substituted aminothiazole prodrugs of compounds with anti-HCV activity | ACHILLION PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090304605-A1 | Substituted Aminothiazole Prodrugs of Compounds with Anti-HCV Activity | ACHILLION PHARMACEUTICALS, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090304605-A1 | Substituted Aminothiazole Prodrugs of Compounds with Anti-HCV Activity | ACHILLION PHARMACEUTICALS, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20080145354-A1 | PEGYLATION OF THERAPEUTIC AGENTS | UNIVERSITY OF SOUTH CAROLINA | 2008-06-19 | — | — | US | disclosed |
| EP-0115613-B1 | DNA SEQUENCES, THEIR PREPARATION, PLASMIDS CONTAINING THESE SEQUENCES AND THEIR USE IN THE SYNTHESIS OF EUKARYOTIC GENE PRODUCTS IN PROKARYOTES | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1991-03-27 | — | — | EP | disclosed |