Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 2/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 2/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 2/20 | 1.00 |
| ▸ | HTR2C | P28335 | 2/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 2/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 2/20 | 1.00 |
| ▸ | DRD1 | P21728 | 13/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802411 | 1.00 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| SCHEMBL9802307 | 1.00 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| Hydrochloric Acid SCHEMBL9802020 | 0.99 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| Hydrochloric Acid SCHEMBL9802211 | 0.99 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| SCHEMBL10380334 | 0.87 | DRD1 (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| SCHEMBL19464266 | 0.87 | DRD1 (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| SCHEMBL7447363 | 0.87 | DRD1 (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| SCHEMBL31018017 | 0.87 | DRD1 (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| SCHEMBL399278 | 0.87 | DRD1 (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C | |
| SCHEMBL30734435 | 0.87 | DRD1 (1.00) | ADRA2AADRA2BADRA2CADRA1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994486-A | Neurological disorders | ABBOTT LABORATORIES (US) | 1991-02-19 | — | — | US | disclosed |