Sorbitol

Sorbitol

SCHEMBL9802569

CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c1ccccc1)O[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c1ccccc1)CC(C)(C)c1ccccc1)c1ccccc1.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
KIF11 P52732 2/20 0.33
TDP1 Q9NUW8 2/20 0.32
MAPK1 P28482 3/20 0.32
MAPT P10636 3/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TRPA1 O75762 1/20 0.32
GAA P10253 1/20 0.32
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 2/20 0.30
PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E968 SCHEMBL22472350 0.94 TAAR1 (0.39) TAAR1ALDH1A1ALOX15KIF11MAPK1
SCHEMBL55578 0.83 TAAR1 (0.50) TAAR1ALDH1A1ALOX15MAPK1MAPT
Phosphine SCHEMBL9467574 0.82 TAAR1 (0.48) TAAR1ALDH1A1ALOX15MAPK1MAPT
SCHEMBL9144235 0.82 TAAR1 (0.48) TAAR1ALDH1A1ALOX15MAPK1MAPT
Iodide SCHEMBL6625841 0.82 TAAR1 (0.48) TAAR1ALDH1A1ALOX15MAPK1MAPT
SCHEMBL17799783 0.81 TAAR1 (0.41) TAAR1ALDH1A1ALOX15MAPK1MAPT
Inositol SCHEMBL3079466 0.79 TAAR1 (0.42) TAAR1ALDH1A1ALOX15MAPK1MAPT
Phosphoric Acid SCHEMBL6689741 0.78 TAAR1 (0.41) TAAR1LMNAALDH1A1ALOX15MAPK1
Acetic Acid SCHEMBL3397599 0.78 CYP2C19 (0.42) TAAR1ALDH1A1ALOX15KIF11MAPK1
Sulfuric Acid SCHEMBL9177660 0.78 TAAR1 (0.41) TAAR1ALDH1A1ALOX15MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5051460-A Chlorotrifluoroethylene-ethylene copolymer with heat resistant stabilizers, epoxy resins, phosphites and esters AUSIMONT, U.S.A., INC. (US) 1991-09-24 US disclosed
EP-0069195-B1 STABILIZED ETHYLENE/CHLOROTRIFLUOROETHYLENE COPOLYMER COMPOSITION Ausimont, U.S.A., Inc. (US) 1988-08-24 EP disclosed
EP-0154518-A2 Phenolic compound, resin stabilizer containing it, and synthetic resins stabilized thereby SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-11 EP disclosed
US-4539354-A PHOSPHITE DERIVATIVE OF A PHENOL, A GROUP II METAL CARBOXYLATE ANDAN ESTER OF A POLYOL ALLIED CORPORATION (US) 1985-09-03 US disclosed
EP-0069195-A2 Stabilized ethylene/chlorotrifluoroethylene copolymer composition Ausimont, U.S.A., Inc. (US) 1983-01-12 EP disclosed