Phosphoric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	TAAR1	Q96RJ0	1/20	0.41

▸	PTPN1	P18031	1/20	0.40

▸	POLB	P06746	2/20	0.38

▸	CYP2C19	P33261	2/20	0.38

▸	HIF1A	Q16665	1/20	0.38

▸	ALDH1A1	P00352	2/20	0.37

▸	ALOX15	P16050	1/20	0.37

▸	SMN1; SMN2	Q16637	1/20	0.36

▸	TSHR	P16473	3/20	0.36

▸	MAPK1	P28482	1/20	0.35

▸	KMT2A	Q03164	2/20	0.35

▸	MAPT	P10636	1/20	0.35

▸	MEN1	O00255	1/20	0.35

▸	GAA	P10253	1/20	0.35

▸	PKM	P14618	1/20	0.35

▸	PGK1	P00558	1/20	0.34

▸	PGK2	P07205	1/20	0.34

▸	KCNN4	O15554	1/20	0.34

▸	CYP2C9	P11712	1/20	0.34

▸	LMNA	P02545	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Inositol SCHEMBL8443504	0.94	TAAR1 (0.37)	TAAR1PTPN1POLBCYP2C19HIF1A
Phosphoric Acid SCHEMBL5665038	0.90	TAAR1 (0.41)	TAAR1PTPN1POLBCYP2C19HIF1A
SCHEMBL55578	0.89	TAAR1 (0.50)	TAAR1CYP2C19HIF1AALDH1A1ALOX15
Phosphine SCHEMBL9467574	0.87	TAAR1 (0.48)	TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL9144235	0.87	TAAR1 (0.48)	TAAR1CYP2C19HIF1AALDH1A1ALOX15
Iodide SCHEMBL6625841	0.87	TAAR1 (0.48)	TAAR1CYP2C19HIF1AALDH1A1ALOX15
Sulfuric Acid SCHEMBL9177660	0.86	TAAR1 (0.41)	TAAR1CYP2C19HIF1AALDH1A1ALOX15
Acetic Acid SCHEMBL3397599	0.86	CYP2C19 (0.42)	TAAR1CYP2C19HIF1AALDH1A1ALOX15
Inositol SCHEMBL3079466	0.84	TAAR1 (0.42)	TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL1659303	0.83	ITPR3 (0.40)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004085638-A1	PHYTASE PRODUCED FROM CITROBACTER BRAAKII	REPUBLIC OF NATIONAL FISHERIES RESEARCH AND DEVELOPMENT INSTITUTE (KR)	2004-10-07	—	—	WO	disclosed
EP-1170994-A1	TRANSGENIC ANIMALS EXPRESSING SALIVARY PROTEINS	UNIVERSITY OF GUELPH (CA)	2002-01-16	—	—	EP	disclosed
WO-2000064247-A1	TRANSGENIC ANIMALS EXPRESSING SALIVARY PROTEINS	UNIVERSITY OF GUELPH (CA)	2000-11-02	—	—	WO	disclosed
WO-1997021729-A9	METHODS AND COMPOSITIONS FOR MODULATING VESICLE RELEASE	—	1997-11-06	—	—	WO	disclosed
WO-1997021729-A1	METHODS AND COMPOSITIONS FOR MODULATING VESICLE RELEASE	SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US)	1997-06-19	—	—	WO	disclosed
US-5434144-A	Methods of using cyclic polyanionic polyol derivatives for regulating skin wrinkles	THE PROCTER & GAMBLE COMPANY (US)	1995-07-18	—	—	US	disclosed