Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23537595 | 0.98 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2PIM1PIM3MAOA | |
| SCHEMBL5680932 | 0.83 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2PIM1PIM3MAOA | |
| SCHEMBL23537555 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PIM1PIM3 | |
| SCHEMBL9803330 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PIM1PIM3MAOA | |
| SCHEMBL17780886 | 0.69 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2PIM1PIM3MAOA | |
| SCHEMBL23537530 | 0.69 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2PIM1PIM3MAOA | |
| SCHEMBL23537407 | 0.67 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2PIM1PIM3RAB9A | |
| SCHEMBL29824591 | 0.67 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2PIM1PIM3RAB9A | |
| SCHEMBL9803021 | 0.67 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PIM1PIM3MAOA | |
| SCHEMBL19002374 | 0.67 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PIM1PIM3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068334-A | Analgesics and antipyretics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |