Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137154 | 0.80 | KDM4E (0.65) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL5349832 | 0.78 | KDM4E (0.62) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL11064769 | 0.77 | KDM4E (0.61) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL11064771 | 0.77 | KDM4E (0.61) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL10124090 | 0.75 | KDM4E (0.59) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL9924679 | 0.75 | KDM4E (0.59) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL14392991 | 0.75 | KDM4E (0.59) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL24403596 | 0.74 | KDM4E (0.57) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL14489328 | 0.74 | KDM4E (0.57) | LMNAKDM4EKMT2ATHRBALDH1A1 | |
| SCHEMBL5068281 | 0.74 | ALDH1A1 (0.45) | LMNAKDM4EKMT2ATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992518-A | Heat-resistant adhesives; matrix resins; dielectrics; composites; lamination | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4992518-A | Heat-resistant adhesives; matrix resins; dielectrics; composites; lamination | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4861885-A | Allylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid amides | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| US-4861885-A | Allylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid amides | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |