Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802867 | 1.00 | HSD17B10 (0.68) | HSD17B10KDM4ETDP1USP2ESR1 | |
| SCHEMBL9802883 | 1.00 | HSD17B10 (0.68) | HSD17B10KDM4ETDP1USP2ESR1 | |
| Bromide SCHEMBL3345174 | 0.98 | HSD17B10 (0.67) | HSD17B10KDM4ETDP1USP2ESR1 | |
| Bromide SCHEMBL9801855 | 0.98 | HSD17B10 (0.67) | HSD17B10KDM4ETDP1USP2ESR1 | |
| Bromide SCHEMBL9801849 | 0.98 | HSD17B10 (0.67) | HSD17B10KDM4ETDP1USP2ESR1 | |
| Bromide SCHEMBL9802574 | 0.87 | HSD17B10 (0.53) | HSD17B10KDM4ETDP1USP2ESR1 | |
| SCHEMBL8144156 | 0.85 | SLC2A1 (0.52) | HSD17B10KDM4ETDP1USP2ESR1 | |
| Bromide SCHEMBL6210519 | 0.84 | SLC2A1 (0.51) | HSD17B10KDM4ETDP1USP2ESR1 | |
| SCHEMBL8477662 | 0.81 | HSD17B10 (1.00) | HSD17B10KDM4ETDP1USP2ESR1 | |
| SCHEMBL8477667 | 0.81 | HSD17B10 (1.00) | HSD17B10KDM4ETDP1USP2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539150-A | HYPOTENSIVE AGENTS, SULFIDING, CYCLIZATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-09-03 | — | — | US | claimed |
| JP-60069076-A | — | — | None | — | — | JP | disclosed |
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4539150-A | HYPOTENSIVE AGENTS, SULFIDING, CYCLIZATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-09-03 | — | — | US | disclosed |
| JP-S6069076-A | BENZOTHIAZEPINE DERIVATIVE AND PRODUCTION THEREOF | MITSUI TOATSU CHEM INC | 1985-04-19 | — | — | JP | disclosed |
| JP-S0669076-A | — | — | 0001-01-01 | — | — | JP | disclosed |