Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 7/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934852 | 0.82 | PTK2 (0.61) | PTK2TSHRL3MBTL1LMNARAB9A | |
| SCHEMBL7683020 | 0.78 | PTK2 (0.57) | PTK2TSHRL3MBTL1LMNARAB9A | |
| SCHEMBL15592920 | 0.76 | PTK2 (0.54) | PTK2TSHRL3MBTL1LMNARAB9A | |
| SCHEMBL2077313 | 0.74 | PTK2 (1.00) | PTK2TSHRL3MBTL1LMNARAB9A | |
| SCHEMBL9802990 | 0.73 | SMN1; SMN2 (0.57) | PTK2TSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL9803418 | 0.72 | SMN1; SMN2 (0.61) | PTK2TSHRL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9802765 | 0.69 | PTK2 (0.47) | PTK2TSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL7052350 | 0.69 | TSHR (0.74) | PTK2TSHRL3MBTL1LMNARAB9A | |
| SCHEMBL7690471 | 0.69 | CDC7 (0.66) | PTK2TSHRL3MBTL1BRD4BUB1 | |
| SCHEMBL23537356 | 0.68 | PARP1 (0.59) | PTK2TSHRL3MBTL1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068334-A | Analgesics and antipyretics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0338228-A2 | Use of quinoline-2,5-diones in a medicament having an analgesic, antipyretic and/or antiphlogistic activity | Dr. Karl Thomae GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |