SCHEMBL9803237

SCHEMBL9803237

CNc1ccc(C2c3ccc(N(C)C)cc3-c3cc(N(C)C)ccc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.34
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
KMT2A Q03164 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 4/20 0.33
KLKB1 P03952 1/20 0.33
PDGFRB P09619 1/20 0.33
TP53 P04637 3/20 0.31
ALOX15 P16050 3/20 0.31
HSD17B10 Q99714 2/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GFER P55789 1/20 0.31
TERT O14746 1/20 0.31
APP P05067 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6282600 0.86 ALDH1A1 (0.44) ALDH1A1MAPTKMT2ATSHRPDGFRB
SCHEMBL9803812 0.81 ALDH1A1 (0.48) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL10774996 0.81 TSHR (0.41) ALDH1A1MAPTSMN1; SMN2KMT2ATSHR
SCHEMBL9803313 0.80 ALDH1A1 (0.40) ALDH1A1KMT2AGAATSHRALOX15
SCHEMBL4859207 0.80 ALDH1A1 (0.38) ALDH1A1MAPTKMT2AGAATSHR
SCHEMBL4860561 0.77 SLC2A1 (0.49) ALDH1A1MAPTSMN1; SMN2TP53HSD17B10
SCHEMBL9803217 0.77 ALDH1A1 (0.43) ALDH1A1MAPTKMT2AGAATSHR
SCHEMBL9803590 0.77 ALDH1A1 (0.37) ALDH1A1MAPTKMT2ATSHRKLKB1
SCHEMBL22588861 0.76 ALDH1A1 (0.41) ALDH1A1MAPTSMN1; SMN2KMT2ACA1
SCHEMBL9803614 0.74 IGLV6-57 (0.36) ALDH1A1MAPTKMT2ATSHRPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232907-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-03-27 EP disclosed
US-4761396-A BASIC PHTHALIDE DYE REACTS WITH FLUORENE DERIVATIVE AND P-PHENYLENEDIAMINE DERIVATIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-08-02 US disclosed