Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | GSR | P00390 | 9/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL9803591 | 0.88 | GSR (0.54) | CA5ACA5BGSRCA2 | |
| Nitric Acid SCHEMBL9874582 | 0.88 | GSR (0.54) | CA5ACA5BGSRCA2 | |
| Nitric Acid SCHEMBL10744127 | 0.85 | CA5A (0.44) | CA5ACA5BGSRCA2 | |
| Nitric Acid SCHEMBL9875239 | 0.80 | CA5A (0.53) | CA5ACA5BGSRCA2MAPT | |
| SCHEMBL18868463 | 0.73 | — | — | |
| Nitric Acid SCHEMBL234 | 0.73 | — | — | |
| Nitric Acid SCHEMBL10981408 | 0.73 | — | — | |
| SCHEMBL2568029 | 0.73 | — | — | |
| SCHEMBL13889070 | 0.73 | — | — | |
| Nitric Acid SCHEMBL37356 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223440-B1 | A PROCESS FOR THE PRODUCTION OF HIGH ENERGY MATERIAL | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1991-03-06 | — | — | EP | disclosed |
| US-4985584-A | RING OPENING REACTION WITH N2O4 OR N2O5 | SECRETARY OF STATE FOR DEFENCE (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0223440-A1 | A process for the production of high energy material | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1987-05-27 | — | — | EP | disclosed |