SCHEMBL9803758

SCHEMBL9803758

C[Si](C)(C)OC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712009 0.72 ALDH1A1 (0.30)
SCHEMBL1055321 0.72
SCHEMBL5408148 0.71 ALDH1A1 (0.31)
SCHEMBL8056627 0.71
SCHEMBL9068041 0.69 TSHR (0.32)
SCHEMBL338658 0.69
SCHEMBL5323293 0.69
SCHEMBL4100051 0.69
SCHEMBL4645477 0.67
SCHEMBL1086612 0.67 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112876502-B Preparation method of N-trimethylsiloxyethoxycarbonyl-N-methyl-L/D-leucine 上海嘉莱多生物技术有限责任公司 2022-01-11 CN claimed
CN-113073010-A Preparation method of multifunctional plant essential oil 吉安市中香天然植物有限公司 2021-07-06 CN claimed
CN-112876502-A Preparation method of N-trimethylsiloxyethoxycarbonyl-N-methyl-L/D-leucine 上海嘉莱多生物技术有限责任公司 2021-06-01 CN claimed
CN-112876502-B Preparation method of N-trimethylsiloxyethoxycarbonyl-N-methyl-L/D-leucine 上海嘉莱多生物技术有限责任公司 2022-01-11 CN disclosed
CN-112876502-A Preparation method of N-trimethylsiloxyethoxycarbonyl-N-methyl-L/D-leucine 上海嘉莱多生物技术有限责任公司 2021-06-01 CN disclosed
EP-0209586-B1 ANTI-HISTAMINE ANTIBODY PREPARATION WITH SPECIFICITY FOR A 4-(2-AMINOETHYL)IMIDAZOLYL GROUP ATTACHED DIRECTLY TO AN ALKYLENE CHAIN AND IMMUNOASSAY METHOD EMPLOYING THE PREPARATION PHARMACIA AB (SE) 1991-03-27 EP disclosed
US-4797370-A ANTIGENS, BONDING, IMMUNOLOGY PHARMACIA AB (SE) 1989-01-10 US disclosed
EP-0209586-A1 ANTI-HISTAMINE ANTIBODY PREPARATION WITH SPECIFICITY FOR A 4-(2-AMINOETHYL)IMIDAZOLYL GROUP ATTACHED DIRECTLY TO AN ALKYLENE CHAIN AND IMMUNOASSAY METHOD EMPLOYING THE PREPARATION. PHARMACIA AB (SE) 1987-01-28 EP disclosed
EP-0208776-A1 CARRIER-BOUND HISTAMINE, ITS MANUFACTURE AND ITS USE PHARMACIA AB (SE) 1987-01-21 EP disclosed
WO-1986004420-A1 ANTIBODY PREPARATION WITH SPECIFICITY FOR ALIPHATICALLY BOUND 4-(2-AMINOETHYL)IMIDAZOLYL GROUP, MANUFACTURE AND USE OF THE ANTIBODY PREPARATION PHARMACIA AB (SE) 1986-07-31 WO disclosed
WO-1986004331-A1 CARRIER-BOUND HISTAMINE, ITS MANUFACTURE AND ITS USE PHARMACIA AB (SE) 1986-07-31 WO disclosed