Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389252 | 0.68 | HSD17B10 (0.46) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL2996567 | 0.67 | ALDH1A1 (0.44) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL9479424 | 0.64 | HSD17B10 (0.41) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL14803714 | 0.62 | ALDH1A1 (0.38) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL890970 | 0.62 | HSD17B10 (0.42) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| Phenanthrene SCHEMBL29358486 | 0.61 | CYP2A6 (1.00) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| Phenanthrene SCHEMBL30932938 | 0.61 | CYP2A6 (1.00) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| Phenanthrene SCHEMBL7643 | 0.61 | CYP2A6 (1.00) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| Phenanthrene SCHEMBL29477074 | 0.61 | CYP2A6 (1.00) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| Phenanthrene SCHEMBL8873977 | 0.61 | CYP2A6 (1.00) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | claimed |
| EP-0335636-A1 | Antiviral compounds | SYNPHAR LABORATORIES INC. (CA) | 1989-10-04 | — | — | EP | claimed |
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |