Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.45 |
| ▸ | CCND1 | P24385 | 4/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479213 | 1.00 | CDK4 (0.45) | CDK4CCND1NOTUMSMN1; SMN2PBRM1 | |
| SCHEMBL29479212 | 1.00 | CDK4 (0.45) | CDK4CCND1NOTUMSMN1; SMN2PBRM1 | |
| SCHEMBL3334605 | 0.79 | CDK4 (0.39) | CDK4CCND1NOTUMSMN1; SMN2PBRM1 | |
| SCHEMBL29236 | 0.77 | SLC6A2 (0.41) | CDK4CCND1NOTUMSMN1; SMN2PBRM1 | |
| SCHEMBL11787645 | 0.76 | CDK4 (0.54) | CDK4CCND1NOTUML3MBTL1HTR2A | |
| SCHEMBL29479215 | 0.72 | HTR2A (0.45) | CDK4CCND1HTR2AHTR2CALDH1A1 | |
| SCHEMBL29812 | 0.69 | CDK4 (0.56) | CDK4CCND1NOTUMHTR2AHTR2C | |
| SCHEMBL29384135 | 0.69 | CDK4 (0.56) | CDK4CCND1NOTUMHTR2AHTR2C | |
| SCHEMBL598296 | 0.68 | SLC6A2 (0.47) | CDK4CCND1NOTUMSLC6A2 | |
| SCHEMBL321199 | 0.68 | CDK4 (0.45) | CDK4CCND1NOTUMSMN1; SMN2PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543304-B | Method for synthesizing metallocene catalyst | 中国科学院上海高等研究院 | 2020-03-31 | — | — | CN | disclosed |
| CN-107820494-A | Nuclear receptor modulators | 艾伯维公司 | 2018-03-20 | — | — | CN | disclosed |
| US-7358398-B2 | of aromatic groups using transition metal catalysis in compressed carbon dioxide; intermediates | ASTRAZENECA UK LIMITED (GB) | 2008-04-15 | — | — | US | disclosed |
| US-20070179315-A1 | Methods of amination | ASTRAZENECA UK LIMITED (GB) | 2007-08-02 | — | — | US | disclosed |
| EP-0413464-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-20 | — | — | EP | disclosed |
| EP-0413465-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-20 | — | — | EP | disclosed |
| EP-0405786-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-02 | — | — | EP | disclosed |
| US-4981827-A | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-01 | — | — | US | disclosed |
| EP-0323082-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179315-A1 | Methods of amination | C5, CBR3, CCNL2 | CDK4 2114/4885CCND1 432/4885NOTUM 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.