Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.45 |
| ▸ | CCND1 | P24385 | 4/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614841 | 1.00 | CDK4 (0.45) | CDK4CCND1NOTUMSMN1; SMN2HTR2A | |
| Hydrochloric Acid SCHEMBL7218572 | 0.98 | CDK4 (0.43) | CDK4CCND1NOTUMSMN1; SMN2HTR2A | |
| Formamide SCHEMBL28452735 | 0.89 | NOTUM (0.41) | CDK4CCND1NOTUMSMN1; SMN2HTR2A | |
| Trifluoroacetic Acid SCHEMBL7401383 | 0.83 | NOTUM (0.44) | NOTUMSMN1; SMN2ALDH1A1KMT2ATSHR | |
| SCHEMBL10932323 | 0.83 | CDK4 (0.42) | CDK4CCND1NOTUMHTR2AHTR2C | |
| SCHEMBL3576716 | 0.78 | CDK4 (0.47) | CDK4CCND1NOTUMHTR2AHTR2C | |
| SCHEMBL30233726 | 0.78 | CDK4 (0.47) | CDK4CCND1NOTUMHTR2AHTR2C | |
| SCHEMBL4288131 | 0.77 | CDK4 (0.45) | CDK4CCND1NOTUMHTR2AHTR2C | |
| SCHEMBL22769564 | 0.77 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5ALDH1A1 | |
| SCHEMBL6530754 | 0.77 | CDK4 (0.45) | CDK4CCND1NOTUMHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122004225-A | Application of 1-methoxyindole in preventing and treating nematodes and nematicide | 浙江大学 | 2026-05-12 | — | — | CN | claimed |
| US-20260047577-A1 | USE OF 1-METHOXYINDOLE FOR REPELLING AND/OR KILLING PESTS | UNIV ZHEJIANG (CN) | 2026-02-19 | — | — | US | claimed |
| CN-119014415-A | Application of 1-methoxyindole in repelling and/or killing pests | 浙江大学 | 2024-11-26 | — | — | CN | claimed |
| CN-115650973-B | Synthesis method and application of NSC69187 derivative compound | 南方医科大学 | 2024-04-16 | — | — | CN | claimed |
| CN-116554272-A | Novel anti-wrinkle hexapeptide compound and preparation method thereof | 杭州湃肽生化科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| US-20230192660-A1 | Protease Inhibitors for Treatment or Prevention of Coronavirus Disease | UNIV LELAND STANFORD JUNIOR (US) | 2023-06-22 | — | — | US | claimed |
| EP-4146267-A1 | PROTEASE INHIBITORS FOR TREATMENT OR PREVENTION OF CORONAVIRUS DISEASE | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-03-15 | — | — | EP | claimed |
| CN-110840896-B | Preparation method and application of dihydro quinazolinone medicine | 三峡大学 | 2022-05-03 | — | — | CN | claimed |
| WO-2021226546-A1 | PROTEASE INHIBITORS FOR TREATMENT OR PREVENTION OF CORONAVIRUS DISEASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-11-11 | — | — | WO | claimed |
| CN-111303125-A | Methoxy-substituted indole-pyrimidine compound and preparation method thereof | 天津法莫西医药科技有限公司 | 2020-06-19 | — | — | CN | claimed |
| EP-3490983-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | Bristol-Myers Squibb Company (US) | 2019-06-05 | — | — | EP | claimed |
| WO-2018026620-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-02-08 | — | — | WO | claimed |
| US-7847152-B2 | Use of tryptophan indole and anthranilate analogs as plant transformation selection agents | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-12-07 | — | — | US | claimed |
| US-20040167119-A1 | 2-(aminomethyl) arylamide analgesics | PHARMACOPEIA, INC (US) | 2004-08-26 | — | — | US | claimed |
| WO-2004071445-A2 | 2-(AMINOMETHYL)ARYLAMIDE ANALGESICS | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2004-08-26 | — | — | WO | claimed |
| EP-0833818-A1 | CB 2? RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1998-04-08 | — | — | EP | claimed |
| EP-0574494-A4 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 1994-07-06 | — | — | EP | claimed |
| EP-0574494-A1 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-12-22 | — | — | EP | claimed |
| WO-1992014732-A1 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-09-03 | — | — | WO | claimed |
| US-4076537-A | Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192660-A1 | Protease Inhibitors for Treatment or Prevention of Coronavirus Disease | ACE, ACE2, PEPD | CDK4 1537/4885CCND1 3664/4885NOTUM 239/4885 |
| US-20260047577-A1 | USE OF 1-METHOXYINDOLE FOR REPELLING AND/OR KILLING PESTS | MIF, IDO1, IDO2 | CDK4 4041/4885CCND1 2257/4885NOTUM 368/4885 |
| US-20040167119-A1 | 2-(aminomethyl) arylamide analgesics | OPRL1, OPRM1, OPRK1 | CDK4 3123/4885CCND1 3963/4885NOTUM 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.